Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation
![Transcription-independent regulation of STING activation and innate immune responses by IRF8 in monocytes | Nature Communications Transcription-independent regulation of STING activation and innate immune responses by IRF8 in monocytes | Nature Communications](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41467-022-32401-1/MediaObjects/41467_2022_32401_Fig1_HTML.png)
Transcription-independent regulation of STING activation and innate immune responses by IRF8 in monocytes | Nature Communications
Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation
![Engineering the Immune Adaptor Protein STING as a Functional Carrier - Sun - 2021 - Advanced Therapeutics - Wiley Online Library Engineering the Immune Adaptor Protein STING as a Functional Carrier - Sun - 2021 - Advanced Therapeutics - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/3122bcd6-da9c-4e9d-95cb-6447008f1862/adtp202100066-fig-0002-m.jpg)
Engineering the Immune Adaptor Protein STING as a Functional Carrier - Sun - 2021 - Advanced Therapeutics - Wiley Online Library
![Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation - ScienceDirect Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S2211124719304371-gr2.jpg)
Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation - ScienceDirect
![Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation - ScienceDirect Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S2211124719304371-fx1.jpg)
Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation - ScienceDirect
![TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells - ScienceDirect TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S2211124720303703-fx1.jpg)
TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells - ScienceDirect
Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation
Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation
![TBK1 recruitment to STING activates both IRF3 and NF-κB that mediate immune defense against tumors and viral infections | PNAS TBK1 recruitment to STING activates both IRF3 and NF-κB that mediate immune defense against tumors and viral infections | PNAS](https://www.pnas.org/cms/10.1073/pnas.2100225118/asset/db848d79-1de7-4bc4-bde9-b07b4a767884/assets/images/large/pnas.2100225118fig05.jpg)
TBK1 recruitment to STING activates both IRF3 and NF-κB that mediate immune defense against tumors and viral infections | PNAS
![GRA15 promotes activation of STING. A, Diagram detailing STING domains... | Download Scientific Diagram GRA15 promotes activation of STING. A, Diagram detailing STING domains... | Download Scientific Diagram](https://www.researchgate.net/publication/335206332/figure/fig3/AS:792502516858881@1565958732688/GRA15-promotes-activation-of-STING-A-Diagram-detailing-STING-domains-CBD-and-CTT-and.jpg)
GRA15 promotes activation of STING. A, Diagram detailing STING domains... | Download Scientific Diagram
Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation
Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation
![miniCTT mediates activation of DCs. (A) BFP and CD86 expression in DCs... | Download Scientific Diagram miniCTT mediates activation of DCs. (A) BFP and CD86 expression in DCs... | Download Scientific Diagram](https://www.researchgate.net/publication/316843590/figure/fig5/AS:1091459621101624@1637235660787/miniCTT-mediates-activation-of-DCs-A-BFP-and-CD86-expression-in-DCs-4-d-after.jpeg)
miniCTT mediates activation of DCs. (A) BFP and CD86 expression in DCs... | Download Scientific Diagram
Targeting Stimulator of Interferon Genes (STING): A Medicinal Chemistry Perspective | Journal of Medicinal Chemistry
![STING is an essential mediator of the Ku70-mediated production of IFN-λ1 in response to exogenous DNA | Science Signaling STING is an essential mediator of the Ku70-mediated production of IFN-λ1 in response to exogenous DNA | Science Signaling](https://www.science.org/cms/10.1126/scisignal.aah5054/asset/9740249a-b5ff-4887-8378-d729d3b87f42/assets/graphic/aah5054-f1.jpeg)
STING is an essential mediator of the Ku70-mediated production of IFN-λ1 in response to exogenous DNA | Science Signaling
![Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation - ScienceDirect Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S2211124719304371-gr5.jpg)